Monday

190422

The Cardinal Sins of Skewed Research, Part 4: Bait and Switch

Drs. Mary Dan and Michael Eades continue their series on the cardinal sins of scientific research, reviewing the bait-and-switch methods researchers often employ to earn or redirect attention. They discuss how statin manufacturers shifted their desired endpoints, turning their focus to cholesterol reduction (regardless of whether such reduction is shown to improve health) rather than the actual prevention of cardiovascular events in order to justify drug prescriptions. The technique of p-value hacking is also considered.

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